Can One Live as Long as 195-Year-Old Tortoises?
Scientists examining Jonathan's genome found that some of his body's biological mechanisms are linked to longevity. These include genes associated with DNA damage repair, metabolic regulation, and protection against cancer.
By examining Jonathan's genome, scientists found that some biological mechanisms of his body are related to longevity. Among these features, we can mention genes related to repairing DNA damage, regulating metabolism and protecting against cancer.
According to Ambassador Arjan, quoted by Jam Jam, Jonathan, the oldest living land animal known in the world, is on the threshold of 195 years old, and researchers hope that examining his genetic characteristics will help discover ways to increase human life span.
One of the interesting research findings is related to mitochondria. These cellular structures provide the energy needed by the cells, and their loss of function is related to aging and aging-related diseases. Investigations showed that the chemical patterns associated with mitochondrial function in Jonathan were similar to samples from much younger turtles. Of course, it is not yet clear how much this feature played a role in his exceptional life.
The researchers also identified differences in the mechanism of DNA repair and telomere maintenance. Telomeres are protective segments at the ends of chromosomes that shorten with age. Some of Jonathan's genes are also similar to long-lived species such as naked blind mice, which are known for their long life and resistance to cancer.
Jonathan lives on the remote island of St. Helena in the South Atlantic. The exact date of his birth is not known, but he was fully grown when he was transferred to this island in 1882. For this reason, his birth year is estimated around 1832; That is, before Queen Victoria came to the throne.
Despite cataracts and loss of sense of smell, he continues to live. Veterinary care and proper nutrition have also been effective in maintaining his health.
Scientists emphasize that it is still not possible to draw a definite conclusion from these findings to increase human lifespan. However, studying animals that live very long may provide medical science with valuable clues about how to combat aging and age-related diseases.
By inhibiting a protein that increases with age, Stanford University researchers succeeded in restoring the lost cartilage in the knees of old mice and reducing the risk of arthritis after knee injury. The promising response of human cartilage samples has also raised the question of whether it will be possible to repair damaged cartilage without joint replacement in the future.
In a new study, researchers found that combining mebendazole, an anthelmintic drug, with gefitinib, a targeted lung cancer drug, can slow the growth of treatment-resistant tumors in preclinical trials.
The chairman of the 12th Lung and Special Care Congress, emphasizing the role of smoking and air pollution in the occurrence of lung diseases and cancer, said: Among cancers, no cancer in Iran and the whole world is more deadly than lung cancer.
According to the results of a large international study, the number of people diagnosed with dementia (dementia) worldwide each year may increase from 11.4 million people in 2023 to more than double that is 24.7 million people by 2050.
A new research has associated the continuous use of eyelash extensions with an increase in demodex mites, eye irritation and eyelid gland disorders.
Statins are one of the most commonly prescribed drug groups. Although these drugs are commonly known for lowering cholesterol, it has been found that the brain may also benefit from them.
Scientists have developed a model that shows that gut bacteria play a surprising role in calorie intake; This means that food labels may not tell the whole truth.