Scientists created a chip to produce microbubbles with the ability to deliver targeted drugs

In this system, ultrasonic waves cause the bubbles to intensify and create vibrations that move the surrounding fluid. The post Scientists made a chip to produce microbubbles capable of targeted drug delivery appeared first on Safir Arjan.

In this system, ultrasonic waves cause the bubbles to intensify and create vibrations that move the surrounding fluid.

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Cornell University researchers have developed a chip-based system that can generate and control hydrogen microbubbles on demand. By directing bubbles to manipulate fluid flow, this technology could pave the way for applications such as targeted drug delivery.

In the experiments, the researchers used sound waves to move the bubbles that were in a 3 mm area on the chip. The purpose of this work was to control the flow of liquids. The device produced the bubbles on a grid of electrodes that allowed them to be electrically controlled.

This new system can be programmed on the fly, and researchers are now able to produce individual bubbles at exactly the desired time and place, adjust their size and number, and change their direction with electronic control. They can control the movement of bubbles individually or in larger groups. This feature allows them to direct the liquid flow in the desired direction.

According to researchers, this technology can have medical applications; Because it paves the way for the construction of microfluidic devices that may enable precise drug delivery.

"With this bubble array, we can control the size, number and position of the bubbles in real time, and thus program the flow direction," said Zhiyuan Zhang, the author of the study.

Zhang used a chip developed at Cornell University's Center for Nanoscale Technology. This chip consists of 9 small electrodes arranged in a square shape and produces bubbles with a size of 10 to 100 micrometers.

To produce a hydrogen bubble, he split the water molecule using an electric current. The longer the voltage was applied, the larger the bubble became. After producing the bubble, the researcher introduced sound energy into the system. These ultrasonic waves intensify the oscillation of the bubbles and by creating vibration, they move the liquid around them.

Bubble size is critical when controlling liquid flow, the researchers say. The size of the bubble determines the ultrasonic frequency required to cause resonance. According to them, properly matching the frequency with the bubble size creates a powerful liquid flow.